Research & Insights

Root-cause health research from the Prism team. Gut health, bioenergetics, hormones, and metabolic optimization.

The Complete Guide on How to Fix Thyroid Function Naturally
The Complete Guide on How to Fix Thyroid Function Naturally
The standard approach to poor thyroid function is to test TSH and hand out T4. That misses most of what matters. Your thyroid controls your metabolism, mood, energy and gut health, and it is being ign
Why Do I Crash in the Afternoon? How One Client Fixed His Afternoon Slump, 3 AM Wakes and Food Reactions in 2 Months
Why Do I Crash in the Afternoon? How One Client Fixed His Afternoon Slump, 3 AM Wakes and Food Reactions in 2 Months
ALT 95, AST 35 and uric acid 7.4, on a diet that was mostly takeout and seed oils. When he increased choline, which the liver needs to export fat, facial redness he'd had his whole adult life began to
How to Increase Dopamine: Nutrients, Light, Gut Health and the Serotonin Problem
How to Increase Dopamine: Nutrients, Light, Gut Health and the Serotonin Problem
These dopaminergic centers project dopamine, sending it to other parts of the brain. The prefrontal cortex, nucleus accumbens, striatum and pituitary receive dopamine.
Why "Eat Less, Move More" Fails So Often
Why "Eat Less, Move More" Fails So Often
Obesity has quadrupled over the last 50 years. Among people on supervised calorie-restricted diets, more than 80% of the lost weight comes back within 5 years.
How to Lower Cortisol: Signs of Chronic Stress, the HPA Axis, and the Nutrients and Habits That Calm It
How to Lower Cortisol: Signs of Chronic Stress, the HPA Axis, and the Nutrients and Habits That Calm It
If you are searching for how to lower cortisol because you have high cortisol, anxiety, and can't sleep, this guide is for you. It covers the signs of chronic stress, the biological mechanisms behind
Gut Health and Autoimmune Disease: Leaky Gut, Butyrate and 8 Other Causes
Gut Health and Autoimmune Disease: Leaky Gut, Butyrate and 8 Other Causes
Autoimmune diseases can be massively improved, if you know how to approach them properly. Here are 10 key causes of autoimmunity and what to do about them.
Why Am I Always Tired? The Root-Cause Guide to Fatigue, Mitochondria, and Getting Your Energy Back
Why Am I Always Tired? The Root-Cause Guide to Fatigue, Mitochondria, and Getting Your Energy Back
Mitochondria are the engines of your cells, and thus your body. They take food and oxygen, and convert it into usable energy. If they aren't working optimally, your "battery" never charges. Focusing o
The Right Way to Implement and Assess Lab Testing
The Right Way to Implement and Assess Lab Testing
Inflammatory markers are good to know, and you can improve your health by knowing them. But they still just tell you the result, rather than the cause.
How to Get Rid of Dandruff: The Root-Cause Guide to Flakes, Inflammation, and Scalp Health
How to Get Rid of Dandruff: The Root-Cause Guide to Flakes, Inflammation, and Scalp Health
The epidermis has a few layers. The outermost is called the stratum corneum, and under normal conditions it is made up of dead skin cells called corneocytes or keratinocytes.
How to Increase Testosterone Naturally: The Full Root-Cause Guide for Men
How to Increase Testosterone Naturally: The Full Root-Cause Guide for Men
Seed oils lower testosterone. Compared to coconut or olive oil, they lower testosterone-producing enzymes, lower cholesterol in the testicles, and cause testicular oxidative damage. Cholesterol in the
5 Science-Backed Natural Weight Loss Tools That Work Without Changing Your Diet
5 Science-Backed Natural Weight Loss Tools That Work Without Changing Your Diet
Coconut oil has been studied specifically for its effect on belly fat, not weight in general, but waistline circumference. In a clinical trial, participants who added roughly 2.5 teaspoons per day to
Mushrooms Health Benefits: 6 Diseases They Reduce Risk of (And Why Ergothioneine Is the Key)
Mushrooms Health Benefits: 6 Diseases They Reduce Risk of (And Why Ergothioneine Is the Key)
In one study, mushroom consumption cut dementia risk by approximately 75%. What made the finding especially significant: even participants with low overall vegetable intake showed strong protection,
Red Light Therapy for Liver Health: How One Clinical Trial Improved Every Single Marker of Fatty Liver Disease
Red Light Therapy for Liver Health: How One Clinical Trial Improved Every Single Marker of Fatty Liver Disease
60 obese older adults were split into two groups of 30. One group followed the Mediterranean diet. The other followed the Mediterranean diet plus red light therapy.
How to Boost Metabolism Naturally: The Complete Root-Cause Guide
How to Boost Metabolism Naturally: The Complete Root-Cause Guide
Energy metabolism is the process by which your body takes food and turns it into ATP. You break down macronutrients piece by piece, extracting energy at every step until nothing is left.
Taurine Benefits for Brain Health: Alzheimer's Protection, Memory, and Stroke Prevention
Taurine Benefits for Brain Health: Alzheimer's Protection, Memory, and Stroke Prevention
Taurine was likely able to restore this receptor by reducing excitotoxicity. Excitotoxicity is a process where excessive glutamate and calcium accumulate and literally poison neurons. Taurine\
The 7 Core Mechanisms of Longevity: What Actually Drives Aging at the Cellular Level
The 7 Core Mechanisms of Longevity: What Actually Drives Aging at the Cellular Level
Life can be thought of fundamentally as two alternating phases: growth and repair.
Ice Cream Health Benefits: What Multiple Decades of Research Actually Show
Ice Cream Health Benefits: What Multiple Decades of Research Actually Show
The 2018 Harvard dissertation found that ice cream was inversely associated with heart disease. Researchers ran different analyses and checked their work repeatedly trying to make the association disa
Magnesium Benefits: The Ultimate Guide to the Nutrient 75% of People Are Missing
Magnesium Benefits: The Ultimate Guide to the Nutrient 75% of People Are Missing
Trials show magnesium dramatically improves insulin resistance. 382 mg of magnesium (as MgCl2) decreases:
Probiotics and Fat Loss: How Your Gut Bacteria Control Your Metabolism
Probiotics and Fat Loss: How Your Gut Bacteria Control Your Metabolism
This is not a small effect. Same calories. Half the fat gain. The difference was entirely in the gut.
5 Supplements That Actually Improve Mitochondrial Function (And Why Each One Works)
5 Supplements That Actually Improve Mitochondrial Function (And Why Each One Works)
MitoQ is a modified form of coenzyme Q10, designed to help it reach the mitochondria more efficiently. This gives it some remarkable properties.
The Root-Cause Guide to Sleep: Melatonin Benefits, Circadian Rhythm, and Brain Chemistry
The Root-Cause Guide to Sleep: Melatonin Benefits, Circadian Rhythm, and Brain Chemistry
The circadian rhythm is the primary governor of your sleep. If your body doesn\
Calorie Restriction Increases Longevity, But Not Because of Weight Loss
Calorie Restriction Increases Longevity, But Not Because of Weight Loss
This was a landmark 2024 study that examined genetically diverse animals. Nearly 1,000 mice in total. That scale matters, you can\
Male Pattern Baldness Treatment: How Antihistamines Regrow Hair by Targeting the Root Cause
Male Pattern Baldness Treatment: How Antihistamines Regrow Hair by Targeting the Root Cause
Hair loss and male pattern baldness are not isolated genetic problems. They are systemic health issues. Excess histamine is a major driver, and that distinction matters because it opens up treatment
How Red Light Therapy Reduced Arterial Plaque Better Than Statins
How Red Light Therapy Reduced Arterial Plaque Better Than Statins
Red Light Therapy for Fat Loss: What Two Clinical Trials Show
Red Light Therapy for Fat Loss: What Two Clinical Trials Show
Here's the most impressive result in the study. A pretty massive improvement in 4 weeks, no change in diet or exercise at all.
Lactoferrin Benefits for Gut Health: Colon Cancer, Crohn's, Leaky Gut, Candida and Dosing
Lactoferrin Benefits for Gut Health: Colon Cancer, Crohn's, Leaky Gut, Candida and Dosing
A man with severe Crohn's disease moved to the U.S. and lost access to his prescriptions. He began taking 1g/day of lactoferrin supplement in lieu of them. No relapse. Sustained remission. This case a
SIBO and Gut Dysbiosis: A Natural, Root-Cause Approach to Gut Health
SIBO and Gut Dysbiosis: A Natural, Root-Cause Approach to Gut Health
Two simple clues often indicate poor gut health. A coated tongue in the morning, particularly at the back. And consistently foamy urine. If you notice these signs, especially alongside digestive sympt
Zinc Carnosine for Gut Inflammation: Ulcerative Colitis Enema Study Results
Zinc Carnosine for Gut Inflammation: Ulcerative Colitis Enema Study Results
Zinc is known to be depleted in inflammatory bowel conditions. Its levels directly correlate with the severity and stage of the disease. Worse inflammation = lower zinc, universally.
17 Signs of Poor Gut Health: How It May Affect Mood, Skin, Hormones and Energy
17 Signs of Poor Gut Health: How It May Affect Mood, Skin, Hormones and Energy
The gut is a central control hub for inflammation, immune activity, neurotransmission, and hormonal signaling. These gut functions can also impair energy metabolism throughout the body, leading to see